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Summer Research Fellowship Programme of India's Science Academies

Phytochemical Investigation of Vernonia cinerea Less

Dr. Rema Devi B

Assistant Professor, Department of Chemistry, Sree Narayana College, Chengannur

Dr. K.V. Radhakrishnan

Senior Principal Scientist, Organic Chemistry Section, Chemical Scieneces and Technology Division, NIIST (CSIR), Trivandrum

Abstract

Vernonia cinerea is a plant belongs to the Asteraceae family, the largest family of the plant kingdom. In Malayalam it is known as Poovamkurunnila, one of the ten herbs that constitute the group of reputed Ayurvedic medicines ‘Dashapushpa'. The genus is known for its intense purple flowers, edible nature etc. The traditional uses of Asteraceae plants include wound healing, asthma, dysentery, cold and diarrhoea. It is used for treating cancer, gastrointestinal disorders and abortions. It also cures urinary incontinence in children. Certain species have a leguminous property and hence enrich soil fertility. Such species are used to control fever, inflammation, bleeding, swelling and detoxification. This plant also is seen to have therapeutic effects against certain gastrointestinal and skin disorders and also some immunomodulatory effects. It is seen to have supplementary effects on reducing smoking rate, beta endorphin release and oxidative stress biomarkers. Our main objective is to isolate and characterize spectroscopically each compound present in the extraction from the plant.

Keywords: Vernonia Ceneria, Sesqui terpenes, Steroids, lactones, lupinol, stigma sterol, chlorophil.

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