Molecular characterization of Otubain: A probable drug target of Leishmania donovani
Leishmaniasis is one of the protozoan parasite diseases caused by the genus of leishmania. It affects over 150 million people all over the world. The transmission is done by the sandfly, an insect. It has two forms, one is cutaneous leishmaniasis that occurs in skin and mucosal layer and the other one is visceral leishmaniasis that involves internal organs of humans. My work is on visceral leishmaniasis (VL) which is caused by the species of Leishmania donovani. This species has a promastigote form when it is in sandfly but in humans it has amastigote form.